Effect of an internet- and app-based stress intervention compared to online psychoeducation in university students with depressive symptoms: Results of a randomized controlled trial

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Effect of an internet- and app-based stress intervention compared to online psychoeducation in university students with depressive symptoms: Results of a randomized controlled trial. / Harrer, Mathias; Apolinário-Hagen, Jennifer; Fritsche, Lara et al.
In: Internet Interventions, Vol. 24, 100374, 01.04.2021.

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@article{a35d52ea607544ee8363ca139707548f,
title = "Effect of an internet- and app-based stress intervention compared to online psychoeducation in university students with depressive symptoms: Results of a randomized controlled trial",
abstract = "Depression is highly prevalent among university students. Internet-based interventions have been found to be effective in addressing depressive symptoms, but it is open if this also applies to interventions directed at academic stress. It is also largely unclear if the techniques employed in such programs provide significant additional benefits when controlling for non-specific intervention effects. A sample of N = 200 students with elevated levels of depression (CES-D ≥ 16) of a large distance-learning university were randomly assigned to either an Internet- and App-based stress intervention group (IG; n = 100) or an active control group (CG; n = 100) receiving an Internet-based psychoeducational program of equal length. Self-report data was assessed at baseline, post-treatment (7 weeks) and three-month follow-up. The primary outcome was depression (CES-D) post-treatment. Secondary outcomes included mental health outcomes, modifiable risk factors, and academic outcomes. We found significant between-group effects on depressive symptom severity (d = 0.36; 95% CI: 0.08–0.64), as well as behavioral activation (d = 0.61; 95% CI: 0.30–0.91), perceived stress (d = 0.45; 95% CI: 0.18–0.73), anxiety (d = 0.35; 95% CI: 0.03–0.67) and other secondary outcomes post-treatment. Effects on depression were sustained at three-month follow-up. Response rates for depressive symptoms were significantly higher in the IG (26%) than the CG (14%) at post-test (χ2=4.5, p = 0.04), but not at three-month follow-up (p = 0.454). We also found significant effects on relevant academic outcomes, including work impairment (follow-up; d = 0.36), work output (post-treatment; d = 0.27) and work cutback (follow-up; d = 0.36). The intervention was more effective for depressive symptoms compared to the CG, and so controlling for unspecific intervention effects. This suggests that specific techniques of the intervention may provide significant additional benefits on depressive symptoms. Trial registration: German Clinical Trial Registration (DRKS): DRKS00011800 (https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00011800).",
keywords = "App, College students, Depression, Internet intervention, Perceived stress, Randomized controlled trial, Psychology",
author = "Mathias Harrer and Jennifer Apolin{\'a}rio-Hagen and Lara Fritsche and Christel Salewski and Zarski, {Anna Carlotta} and Dirk Lehr and Harald Baumeister and Pim Cuijpers and Ebert, {David Daniel}",
note = "{\textcopyright} 2021 The Authors.",
year = "2021",
month = apr,
day = "1",
doi = "10.1016/j.invent.2021.100374",
language = "English",
volume = "24",
journal = "Internet Interventions",
issn = "2214-7829",
publisher = "Elsevier B.V.",

}

RIS

TY - JOUR

T1 - Effect of an internet- and app-based stress intervention compared to online psychoeducation in university students with depressive symptoms

T2 - Results of a randomized controlled trial

AU - Harrer, Mathias

AU - Apolinário-Hagen, Jennifer

AU - Fritsche, Lara

AU - Salewski, Christel

AU - Zarski, Anna Carlotta

AU - Lehr, Dirk

AU - Baumeister, Harald

AU - Cuijpers, Pim

AU - Ebert, David Daniel

N1 - © 2021 The Authors.

PY - 2021/4/1

Y1 - 2021/4/1

N2 - Depression is highly prevalent among university students. Internet-based interventions have been found to be effective in addressing depressive symptoms, but it is open if this also applies to interventions directed at academic stress. It is also largely unclear if the techniques employed in such programs provide significant additional benefits when controlling for non-specific intervention effects. A sample of N = 200 students with elevated levels of depression (CES-D ≥ 16) of a large distance-learning university were randomly assigned to either an Internet- and App-based stress intervention group (IG; n = 100) or an active control group (CG; n = 100) receiving an Internet-based psychoeducational program of equal length. Self-report data was assessed at baseline, post-treatment (7 weeks) and three-month follow-up. The primary outcome was depression (CES-D) post-treatment. Secondary outcomes included mental health outcomes, modifiable risk factors, and academic outcomes. We found significant between-group effects on depressive symptom severity (d = 0.36; 95% CI: 0.08–0.64), as well as behavioral activation (d = 0.61; 95% CI: 0.30–0.91), perceived stress (d = 0.45; 95% CI: 0.18–0.73), anxiety (d = 0.35; 95% CI: 0.03–0.67) and other secondary outcomes post-treatment. Effects on depression were sustained at three-month follow-up. Response rates for depressive symptoms were significantly higher in the IG (26%) than the CG (14%) at post-test (χ2=4.5, p = 0.04), but not at three-month follow-up (p = 0.454). We also found significant effects on relevant academic outcomes, including work impairment (follow-up; d = 0.36), work output (post-treatment; d = 0.27) and work cutback (follow-up; d = 0.36). The intervention was more effective for depressive symptoms compared to the CG, and so controlling for unspecific intervention effects. This suggests that specific techniques of the intervention may provide significant additional benefits on depressive symptoms. Trial registration: German Clinical Trial Registration (DRKS): DRKS00011800 (https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00011800).

AB - Depression is highly prevalent among university students. Internet-based interventions have been found to be effective in addressing depressive symptoms, but it is open if this also applies to interventions directed at academic stress. It is also largely unclear if the techniques employed in such programs provide significant additional benefits when controlling for non-specific intervention effects. A sample of N = 200 students with elevated levels of depression (CES-D ≥ 16) of a large distance-learning university were randomly assigned to either an Internet- and App-based stress intervention group (IG; n = 100) or an active control group (CG; n = 100) receiving an Internet-based psychoeducational program of equal length. Self-report data was assessed at baseline, post-treatment (7 weeks) and three-month follow-up. The primary outcome was depression (CES-D) post-treatment. Secondary outcomes included mental health outcomes, modifiable risk factors, and academic outcomes. We found significant between-group effects on depressive symptom severity (d = 0.36; 95% CI: 0.08–0.64), as well as behavioral activation (d = 0.61; 95% CI: 0.30–0.91), perceived stress (d = 0.45; 95% CI: 0.18–0.73), anxiety (d = 0.35; 95% CI: 0.03–0.67) and other secondary outcomes post-treatment. Effects on depression were sustained at three-month follow-up. Response rates for depressive symptoms were significantly higher in the IG (26%) than the CG (14%) at post-test (χ2=4.5, p = 0.04), but not at three-month follow-up (p = 0.454). We also found significant effects on relevant academic outcomes, including work impairment (follow-up; d = 0.36), work output (post-treatment; d = 0.27) and work cutback (follow-up; d = 0.36). The intervention was more effective for depressive symptoms compared to the CG, and so controlling for unspecific intervention effects. This suggests that specific techniques of the intervention may provide significant additional benefits on depressive symptoms. Trial registration: German Clinical Trial Registration (DRKS): DRKS00011800 (https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00011800).

KW - App

KW - College students

KW - Depression

KW - Internet intervention

KW - Perceived stress

KW - Randomized controlled trial

KW - Psychology

UR - http://www.scopus.com/inward/record.url?scp=85101848619&partnerID=8YFLogxK

U2 - 10.1016/j.invent.2021.100374

DO - 10.1016/j.invent.2021.100374

M3 - Journal articles

C2 - 33718001

AN - SCOPUS:85101848619

VL - 24

JO - Internet Interventions

JF - Internet Interventions

SN - 2214-7829

M1 - 100374

ER -

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