Professorship for Sustainable Chemistry and Material Resources
Organisational unit: Section
Organisation profile
RESEARCH AND TEACHING
Chair for Sustainable Chemistry and Material Resources
We research and train in the field of sustainable chemistry and pharmacy.
We focus on environmental questions as well as on sustainable questions going beyond that such as social and ecological aspects in the context of the life cycle of chemical substances and products. This includes the extraction of raw material, its use as well as the fate after its use. We are also interested in the material flow associated with the extraction and use of the raw material. On top of the experimental work and modeling, we also develop concepts as for example Benign by Design intended dissipation.
Our research and teaching is carried out on an intra- and transdisciplinary scale within the Faculty of Sustainability together with national and international co-operations.
Topics
We are interested in environmental affairs and all questions concerning the sustainability within the context of the life cycle of chemicals, starting with the raw material itself and going on to the synthesis, the use to end up with the environmental fate of chemical substances and products after their use. Beyond the chemical substances and products themselves, we are also interested in the associated material flows, especially when it comes to the so-called strategic resources (e. g. phosphate, seldom metals).
We investigate the fate (e. g. identification of relevant sources) in the environment as well as the spread and the behavior of chemicals (e. g. spread, biological and photochemical degradation) in the aquatic environment in the sense of a sustainable water management. This is why we want to record their effects (e. g. genotoxicity, mutagenity, and bacteria toxicity).At present we are focusing on pesticides, pharmaceuticals, textile auxiliary agents and nanoparticles.
Service offers
Examination of (bio)-degradability of chemicals and pharmaceuticals
according to OECD/DIN/ISO and others:
• Closed Bottle-Test (OECD 301 D)
• Manometric Respirometry (OECD 301 F)
• Zahn-Wellens-Test (OECD 302 B)
• Waste water treatment plant simulation (OECD 303 A)
• Water Sediment Test
• Photochemical degradation
• Photocatalytic degradation
• Electro coalugation
• and other
Toxicity
Acute and chronic toxicity in bacteria:
• Luminescent bacteria test with Vibrio fischeri (30 minutes and 20h)
• Growth-inhibition test with Pseudomonas putida (16h) and Vibrio fischeri (20h)
• Growth-inhibition test with Enteroccus faecalis
Genotoxicity:
• Ames-Test with Salmonella typhimurium TA 98/TA 100
• Umu-Test with Salmonella typhimurium TA 1535/ psK 1002
• Mikronucleus-Test with CHO-Cells by FACS-Analysis
• Green Screen-Assay with TK6-cells
Chemical informatics
Structure property relationships
• Calculation of physicochemical properties of molecules
• Calculation of quantum chemical parameters of molecules
• Calculation of toxicity and mutagenicity
• Calculation of the biological degradation
• Calculation of metabolites (mammalia bacteria)
• Targeted design of chemicals and pharmaceuticals
• Support in purchasing decisions
• Product optimization
• REACH
Water flux based reactive mass transport modelling and assessment
• Spatio-temporal analysis of discharge and water quality (R-Statistics, SigmaPlot, ArcGIS)
• Assessment of water quality by combined water quality and quantity indices (WQI, WQQI, WAI)
• Water quality modelling in lakes and reservoirs in 1D, 2D and 3D (LAC, MOHID Water, Ce-qual)
• Catchment modelling of hydrology, erosion and sedimenttransport, phosphorus discharge, pesticides and transformation product discharge (ZIN-Sed, MOHID Land, reservoir models)
• River channel modelling of water, sediment, phosphorus, pesticide and transformation product discharge (ZIN-Sed, MOHID Stream)
• Scenario modelling and assessment
• System analysis and management assessment
• Integrated water ressources management
Analytics
• Liquid chromatography coupled to ion trap mass spectrometry
• HPLC with UV and fluorescence detection
• Gas chromatography coupled to mass spectrometry
• Ion chromatography
- Journal articles › Research › Peer-reviewed
- Published
Design of a Master of Science Sustainable Chemistry
Elschami, M. & Kümmerer, K., 01.09.2020, In: Sustainable Chemistry and Pharmacy. 17, 10 p., 100270.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Design rules for environmental biodegradability of phenylalanine alkyl ester linked ionic liquids
Suk, M., Haiß, A., Westphal, J., Jordan, A., Kellett, A., Kapitanov, I. V., Karpichev, Y., Gathergood, N. & Kümmerer, K., 21.07.2020, In: Green Chemistry . 22, 14, p. 4498-4508 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Development and validation of a stability-indicating RP-HPLC method for the determination of paracetamol with dantrolene or/and cetirizine and pseudoephedrine in two pharmaceutical dosage forms
Hadad, G. M., Emara, S. & Mahmoud, W. M. M., 15.10.2009, In: Talanta. 79, 5, p. 1360-1367 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Discharge and fate of biocide residuals to ephemeral stormwater retention pond sediments
Linke, F., Olsson, O., Schnarr, L., Kümmerer, K., Preusser, F., Bork, M., Leistert, H. & Lange, J., 01.11.2022, In: Hydrology Research. 53, 11, p. 1441-1453 13 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Do edible oils reduce bacterial colonization of enamel in situ ?
Hannig, C., Kirsch, J., Al-Ahmad, A., Kensche, A., Hannig, M. & Kümmerer, K., 03.2013, In: Clinical Oral Investigations. 17, 2, p. 649-658 10 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Education in green chemistry and in sustainable chemistry: perspectives towards sustainability
Zuin, V. G., Eilks, I., Elschami, M. & Kümmerer, K., 21.02.2021, In: Green Chemistry . 23, 4, p. 1594-1608 15 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Effect of safflower oil on the protective properties of the in situ formed salivary pellicle
Hannig, C., Wagenschwanz, C., Pötschke, S., Kümmerer, K., Kensche, A., Hoth-Hannig, W. & Hannig, M., 08.2012, In: Caries Research. 46, 5, p. 496-506 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Elution of monomers from provisional composite materials
Schulz, S. D., Laquai, T., Kümmerer, K., Bolek, R., Mersch-Sundermann, V. & Polydorou, O., 01.01.2015, In: International Journal of Polymer Science. 2015, 7 p., 617407.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Elution of monomers from three different bonding systems and their antibacterial effect
Polydorou, O., Rogatti, P., Bolek, R., Wolkewitz, M., Kümmerer, K. & Hellwig, E., 07.2013, In: Odontology / the Society of the Nippon Dental University. 101, 2, p. 170-176 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Enhancement of Capsid Gene Expression: Preparing the Human Papillomavirus Type 16 Major Structural Gene L1 for DNA Vaccination Purposes.
Leder, C., Kleinschmidt, J. A., Wiethe, C. & Müller, M., 01.10.2001, In: Journal of Virology. 75, 19, p. 9201-9209 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Entry of biocides and their transformation products into groundwater via urban stormwater infiltration systems
Hensen, B., Lange, J., Jackisch, N., Zieger, F., Olsson, O. & Kümmerer, K., 01.11.2018, In: Water Research. 144, p. 413-423 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Environmental fate and effect assessment of thioridazine and its transformation products formed by photodegradation
Wilde, M. L., Menz, J., Trautwein, C., Leder, C. & Kümmerer, K., 06.2016, In: Environmental Pollution. 213, p. 658-670 13 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Estimation of phosphorus export from a Mediterranean agricultural catchment with scarce data
Gassmann, M., Brito, D. & Olsson, O., 02.01.2014, In: Hydrological Sciences Journal. 59, 1, p. 221–233 13 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Evaluation of the toxic effects of four anti-cancer drugs in plant bioassays and its potency for screening in the context of waste water reuse for irrigation
Lutterbeck, C. A., Kern, D. I., Machado, Ê. L. & Kümmerer, K., 01.09.2015, In: Chemosphere. 135, p. 403-410 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Experimental and in silico assessment of fate and effects of the antipsychotic drug quetiapine and its bio- and phototransformation products in aquatic environments
Herrmann, M., Menz, J., Gassmann, M., Olsson, O. & Kümmerer, K., 01.11.2016, In: Environmental Pollution. 218, p. 66-76 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Experimental and in silico assessment of fate and effects of the UV filter 2-phenylbenzimidazole 5-sulfonic acid and its phototransformation products in aquatic solutions
Westphal, J., Kümmerer, K. & Olsson, O., 15.03.2020, In: Water Research. 171, 10 p., 115393.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Fate of Pesticides and Their Transformation Products: First Flush Effects in a Semi-Arid Catchment
Olsson, O., Khodorkovsky, M., Gassmann, M., Friedler, E., Schneider, M. & Dubowski, Y., 02.2013, In: Clean - Soil, Air, Water. 41, 2, p. 134-142 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Fatty Acid Profile of the Initial Oral Biofilm (Pellicle): an In-Situ Study
Reich, M., Kümmerer, K., Al-Ahmad, A. & Hannig, C., 09.2013, In: Lipids. 48, 9, p. 929-937 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Fenton process on single and mixture components of phenothiazine pharmaceuticals: Assessment of intermediaries, fate, and preliminary ecotoxicity
Wilde, M. L., Schneider, M. & Kümmerer, K., 01.04.2017, In: The Science of The Total Environment. 583, p. 36-52 17 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Flavonoids as benign substitutes for more harmful synthetic chemicals - effects of flavonoids and their transformation products on algae
Schnarr, L., Olsson, O., Ohls, S., Webersinn, J., Mauch, T. & Kümmerer, K., 01.04.2024, In: Sustainable Chemistry and Pharmacy. 38, 19 p., 101473.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Fluorescent tracers to evaluate pesticide dissipation and transformation in agricultural soils
Lange, J., Olsson, O., Sweeny, B., Herbstritt, B., Reich, M., Alvarez-Zaldivar, P., Payraudeau, S. & Imfeld, G., 01.04.2018, In: The Science of The Total Environment. 619 - 620, p. 1682-1689 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Fragrance allergens in household detergents
Wieck, S., Olsson, O., Kümmerer, K. & Klaschka, U., 01.08.2018, In: Regulatory toxicology and pharmacology : RTP. 97, p. 163-169 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
General strategies to increase the repeatability in non-target screening by liquid chromatography-high resolution mass spectrometry
Bader, T., Schulz, W., Kümmerer, K. & Winzenbacher, R., 07.09.2016, In: Analytica Chimica Acta. 935, p. 173-186 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Genetic toxicology in silico protocol
Hasselgren, C., Ahlberg, E., Akahori, Y., Amberg, A., Anger, L. T., Atienzar, F., Auerbach, S., Beilke, L., Bellion, P., Benigni, R., Bercu, J., Booth, E. D., Bower, D., Brigo, A., Cammerer, Z., Cronin, M. T. D., Crooks, I., Cross, K. P., Custer, L., Dobo, K., Doktorova, T., Faulkner, D., Ford, K. A., Fortin, M. C., Frericks, M., Gad-McDonald, S. E., Gellatly, N., Gerets, H., Gervais, V., Glowienke, S., Van Gompel, J., Harvey, J. S., Hillegass, J., Honma, M., Hsieh, J. H., Hsu, C. W., Barton-Maclaren, T. S., Johnson, C., Jolly, R., Jones, D., Kemper, R., Kenyon, M. O., Kruhlak, N. L., Kulkarni, S. A., Kümmerer, K., Leavitt, P., Masten, S., Miller, S., Moudgal, C., Muster, W., Paulino, A., Lo Piparo, E., Powley, M., Quigley, D. P., Reddy, M. V., Richarz, A. N., Schilter, B., Snyder, R. D., Stavitskaya, L., Stidl, R., Szabo, D. T., Teasdale, A., Tice, R. R., Trejo-Martin, A., Vuorinen, A., Wall, B. A., Watts, P., White, A. T., Wichard, J., Witt, K. L., Woolley, A., Woolley, D., Zwickl, C. & Myatt, G. J., 01.10.2019, In: Regulatory Toxicology and Pharmacology. 107, 104403, 21 p., 104403.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Genotoxic effect of ciprofloxacin during photolytic decomposition monitored by the in vitro micronucleus test (MNvit) in HepG2 cells
Garcia-Käufer, M., Bergheim, M., Gminski, R., Gupta, P., Mathur, N., Kümmerer, K., Mersch-Sundermann, V. & Haddad, T., 06.2012, In: Environmental Science and Pollution Research. 19, 5, p. 1719-1727 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Germany – Europe –World 2042: A Transformative Longitudinal Study
Bergmann, M., Burandt, S., Heinrichs, H., Kümmerer, K. & Lang, D. J., 05.2014, In: GAIA. 23, 2, p. 132-134 3 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Gremlin-1 is an inhibitor of macrophage migration inhibitory factor and attenuates atherosclerotic plaque growth in ApoE-/- mice
Müller, I., Schönberger, T., Schneider, M., Borst, O., Ziegler, M., Seizer, P., Leder, C., Müller, K., Lang, M., Appenzeller, F., Lunov, O., Büchele, B., Fahrleitner, M., Olbrich, M., Langer, H., Geisler, T., Lang, F., Chatterjee, M., de Boer, J. F., Tietge, U. J., Bernhagen, J., Simmet, T. & Gawaz, M., 01.11.2013, In: The Journal of Biological Chemistry. 288, 44, p. 31635-31645 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Growth and fatty acid composition of Acutodesmus obliquus under different light spectra and temperatures
Helamieh, M., Gebhardt, A., Reich, M., Kuhn, F., Kerner, M. & Kümmerer, K., 09.2021, In: Lipids. 56, 5, p. 485-498 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Hazard screening of photo-transformation products from pharmaceuticals: Application to selective β1-blockers atenolol and metoprolol
Toolaram, A. P., Menz, J., Rastogi, T., Leder, C., Kümmerer, K. & Schneider, M., 01.02.2017, In: The Science of The Total Environment. 579, p. 1769-1780 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Helical [n]catamantanes and all-trans-perhydroacenic [n]perimantanes: Structures and von Baeyer IUPAC numbering of carbon atoms
Balaban, A. T. & Rücker, C., 19.12.2013, In: Arkivoc. 2014, 2, p. 346-361 16 p., CV-8352NP.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
High performance liquid chromatographic determination of etofibrate and its hydrolysis products.
El-Gindy, A., Hadad, G. M. & Mahmoud, W. M. M., 04.01.2007, In: Journal of Pharmaceutical and Biomedical Analysis. 43, 1, p. 196–203 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
How data on transformation products can support the redesign of sulfonamides towards better biodegradability in the environment
Puhlmann, N., Olsson, O. & Kümmerer, K., 15.04.2024, In: Science of the Total Environment. 921, 13 p., 171027.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
How to specify the structure of substituted blade-like zigzag diamondoids
Balaban, A. T. & Rücker, C., 09.2013, In: Central European Journal of Chemistry. 11, 9, p. 1423-1430 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Hydraulic fracturing wastewater in Germany: Composition, treatment, concerns
Olsson, O., Weichgrebe, D. & Rosenwinkel, K-H., 12.2013, In: Environmental Earth Sciences . 70, 8, p. 3895-3906 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Hydraulic Fracturing: Zusammensetzung und Entsorgung anfallender Abwässer
Olsson, O., Weichgrebe, D. & Rosenwinkel, K-H., 09.2012, In: Wasser und Abfall. 14, 9, p. 10-15 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Hydrological tracers for assessing transport and dissipation processes of pesticides in a model constructed wetland system
Fernández-Pascual, E., Bork, M., Hensen, B. & Lange, J., 08.01.2020, In: Hydrology and Earth System Sciences. 24, 1, p. 41-60 20 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Identification of a heparin-binding motif on adeno-associated virus type 2 capsids
Kern, A., Schmidt, K., Leder, C., Müller, O., Wobus, C. E., Bettinger, K., von der Lieth, C. W., King, J. A. & Kleinschmidt, J. A., 15.10.2003, In: Journal of Virology. 77, 20, p. 11072–11081 10 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Identification of environmentally biodegradable scaffolds for the benign design of quinolones and related substances
Suk, M., Lorenz, S. & Kümmerer, K., 01.04.2023, In: Sustainable Chemistry and Pharmacy. 31, 100947.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Identification of phototransformation products of thalidomide and mixture toxicity assessment: An experimental and quantitative structural activity relationships (QSAR) approach
Mahmoud, W. M. M., Toolaram, A. P., Menz, J., Leder, C., Schneider, M. & Kümmerer, K., 01.02.2014, In: Water Research. 49, 1, p. 11-22 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Identification of phototransformation products of the antiepileptic drug gabapentin: Biodegradability and initial assessment of toxicity
Herrmann, M., Menz, J., Olsson, O. & Kümmerer, K., 15.11.2015, In: Water Research. 85, p. 11-21 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Identification of structure-biodegradability relationships for ionic liquids - clustering of a dataset based on structural similarity
Amsel, A. K., Olsson, O. & Kümmerer, K., 29.09.2023, In: Green Chemistry . 25, 22, p. 9226-9250 25 p.Research output: Journal contributions › Journal articles › Research › peer-review
- E-pub ahead of print
Impact of green and blue-green light on the growth, pigment concentration, and fatty acid unsaturation in the microalga Monoraphidium braunii
Helamieh, M., Reich, M., Rohne, P., Riebesell, U., Kerner, M. & Kümmerer, K., 26.10.2023, (E-pub ahead of print) In: Photochemistry and Photobiology. 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Incomplete aerobic degradation of the antidiabetic drug Metformin and identification of the bacterial dead-end transformation product Guanylurea
Trautwein, C. & Kümmerer, K., 10.2011, In: Chemosphere. 85, 5, p. 765-773 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Inhibition of foam cell formation using a soluble CD68-Fc fusion protein
Daub, K., Siegel-Axel, D., Schönberger, T., Leder, C., Seizer, P., Müller, K., Schaller, M., Penz, S., Menzel, D., Buchele, B., Bültmann, A., Münch, G., Lindemann, S., Simmet, T. & Gawaz, M., 09.2010, In: Journal of Molecular Medicine. 88, 9, p. 909-920 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Initial fate assessment of teratogenic drug trimipramine and its photo-transformation products - Role of pH, concentration and temperature
Khaleel, N. D. H., Mahmoud, W. M. M., Olsson, O. & Kümmerer, K., 01.01.2017, In: Water Research. 108, p. 197-211 15 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Initial hazard screening for genotoxicity of photo-transformation products of ciprofloxacin by applying a combination of experimental and in-silico testing
Toolaram, A. P., Haddad, T., Leder, C. & Kümmerer, K., 04.2016, In: Environmental Pollution. 211, p. 148-156 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
In search of the Holy Grail of Rodent control: Step-by-step implementation of safe and sustainable-by-design principles on the example of rodenticides
Hohenberger, J., Friesen, A., Wieck, S. & Kümmerer, K., 01.04.2022, In: Sustainable Chemistry and Pharmacy. 25, 19 p., 100602.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
In silico toxicology protocols
Myatt, G. J., Ahlberg, E., Akahori, Y., Allen, D., Amberg, A., Anger, L. T., Aptula, A., Auerbach, S., Beilke, L., Bellion, P., Benigni, R., Bercu, J., Booth, E. D., Bower, D., Brigo, A., Burden, N., Cammerer, Z., Cronin, M. T. D., Cross, K. P., Custer, L., Dettwiler, M., Dobo, K., Ford, K. A., Fortin, M. C., Gad-McDonald, S. E., Gellatly, N., Gervais, V., Glover, K. P., Glowienke, S., Van Gompel, J., Gutsell, S., Hardy, B., Harvey, J. S., Hillegass, J., Honma, M., Hsieh, J. H., Hsu, C. W., Hughes, K., Johnson, C., Jolly, R., Jones, D., Kemper, R., Kenyon, M. O., Kim, M. T., Kruhlak, N. L., Kulkarni, S. A., Kümmerer, K., Leavitt, P., Majer, B., Masten, S., Miller, S., Moser, J., Mumtaz, M., Muster, W., Neilson, L., Oprea, T. I., Patlewicz, G., Paulino, A., Lo Piparo, E., Powley, M., Quigley, D. P., Reddy, M. V., Richarz, A. N., Ruiz, P., Schilter, B., Serafimova, R., Simpson, W., Stavitskaya, L., Stidl, R., Suarez-Rodriguez, D., Szabo, D. T., Teasdale, A., Trejo-Martin, A., Valentin, J. P., Vuorinen, A., Wall, B. A., Watts, P., White, A. T., Wichard, J., Witt, K. L., Woolley, A., Woolley, D., Zwickl, C. & Hasselgren, C., 01.07.2018, In: Regulatory toxicology and pharmacology : RTP. 96, p. 1-17 17 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Inventory of biodegradation data of ionic liquids
Amsel, A. K., Olsson, O. & Kümmerer, K., 01.07.2022, In: Chemosphere. 299, 134385.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Ionic liquids vs. ethanol as extraction media of algicidal compounds from mango processing waste
Segatto, M. L., Schnarr, L., Olsson, O., Kümmerer, K. & Zuin, V. G., 16.09.2022, In: Frontiers in Chemistry. 10, 13 p., 986987.Research output: Journal contributions › Journal articles › Research › peer-review