Professorship for Sustainable Chemistry and Material Resources
Organisational unit: Section
Organisation profile
RESEARCH AND TEACHING
Chair for Sustainable Chemistry and Material Resources
We research and train in the field of sustainable chemistry and pharmacy.
We focus on environmental questions as well as on sustainable questions going beyond that such as social and ecological aspects in the context of the life cycle of chemical substances and products. This includes the extraction of raw material, its use as well as the fate after its use. We are also interested in the material flow associated with the extraction and use of the raw material. On top of the experimental work and modeling, we also develop concepts as for example Benign by Design intended dissipation.
Our research and teaching is carried out on an intra- and transdisciplinary scale within the Faculty of Sustainability together with national and international co-operations.
Topics
We are interested in environmental affairs and all questions concerning the sustainability within the context of the life cycle of chemicals, starting with the raw material itself and going on to the synthesis, the use to end up with the environmental fate of chemical substances and products after their use. Beyond the chemical substances and products themselves, we are also interested in the associated material flows, especially when it comes to the so-called strategic resources (e. g. phosphate, seldom metals).
We investigate the fate (e. g. identification of relevant sources) in the environment as well as the spread and the behavior of chemicals (e. g. spread, biological and photochemical degradation) in the aquatic environment in the sense of a sustainable water management. This is why we want to record their effects (e. g. genotoxicity, mutagenity, and bacteria toxicity).At present we are focusing on pesticides, pharmaceuticals, textile auxiliary agents and nanoparticles.
Service offers
Examination of (bio)-degradability of chemicals and pharmaceuticals
according to OECD/DIN/ISO and others:
• Closed Bottle-Test (OECD 301 D)
• Manometric Respirometry (OECD 301 F)
• Zahn-Wellens-Test (OECD 302 B)
• Waste water treatment plant simulation (OECD 303 A)
• Water Sediment Test
• Photochemical degradation
• Photocatalytic degradation
• Electro coalugation
• and other
Toxicity
Acute and chronic toxicity in bacteria:
• Luminescent bacteria test with Vibrio fischeri (30 minutes and 20h)
• Growth-inhibition test with Pseudomonas putida (16h) and Vibrio fischeri (20h)
• Growth-inhibition test with Enteroccus faecalis
Genotoxicity:
• Ames-Test with Salmonella typhimurium TA 98/TA 100
• Umu-Test with Salmonella typhimurium TA 1535/ psK 1002
• Mikronucleus-Test with CHO-Cells by FACS-Analysis
• Green Screen-Assay with TK6-cells
Chemical informatics
Structure property relationships
• Calculation of physicochemical properties of molecules
• Calculation of quantum chemical parameters of molecules
• Calculation of toxicity and mutagenicity
• Calculation of the biological degradation
• Calculation of metabolites (mammalia bacteria)
• Targeted design of chemicals and pharmaceuticals
• Support in purchasing decisions
• Product optimization
• REACH
Water flux based reactive mass transport modelling and assessment
• Spatio-temporal analysis of discharge and water quality (R-Statistics, SigmaPlot, ArcGIS)
• Assessment of water quality by combined water quality and quantity indices (WQI, WQQI, WAI)
• Water quality modelling in lakes and reservoirs in 1D, 2D and 3D (LAC, MOHID Water, Ce-qual)
• Catchment modelling of hydrology, erosion and sedimenttransport, phosphorus discharge, pesticides and transformation product discharge (ZIN-Sed, MOHID Land, reservoir models)
• River channel modelling of water, sediment, phosphorus, pesticide and transformation product discharge (ZIN-Sed, MOHID Stream)
• Scenario modelling and assessment
• System analysis and management assessment
• Integrated water ressources management
Analytics
• Liquid chromatography coupled to ion trap mass spectrometry
• HPLC with UV and fluorescence detection
• Gas chromatography coupled to mass spectrometry
• Ion chromatography
- Published
Antineoplastic compounds in the environment: Substances of special concern
Kümmerer, K., Haiß, A., Schuster, A., Hein, A. & Ebert, I., 01.08.2016, In: Environmental Science and Pollution Research. 23, 15, p. 14791–14804 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Biodegradation screening of chemicals in an artificial matrix simulating the water-sediment interface
Baginska, E., Haiß, A. & Kümmerer, K., 01.01.2015, In: Chemosphere. 119, p. 1240-1246 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Metabolites and Transformation Products of Pharmaceuticals in the Aquatic Environment as Contaminants of Emerging Concern
Michael, I., Vasquez Hadjilyra, M. I., Hapeshi, E., Haddad, T., Baginska, E., Kümmerer, K. & Fatta-Kassinos, D., 01.01.2014, Transformation Products of Emerging Contaminants in the Environment: Analysis, Processes, Occurrence, Effects and Risks. Lambropoulou, D. A. & Nollet, L. M. (eds.). Chichester: Wiley-VCH Verlag, p. 413-458 46 p.Research output: Contributions to collected editions/works › Chapter › peer-review
- Published
Ecotoxicological evaluation of selected anticancer drugs
Lutterbeck, C., Kern, D. I., Machado, Ê. L. & Kümmerer, K., 10.09.2014, In: Toxicology Letters. 229, Supplement, p. S71-S72 2 p.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- Published
Evaluation of the effects of four cytotoxic compounds against plant seedlings
Lutterbeck, C., Kern, D. I., Machado, Ê. L. & Kümmerer, K., 10.09.2014, In: Toxicology Letters. 229, Supplement, p. S71-S71 1 p.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- Published
Design of new environmentally benign pharmaceutically active compounds
Kümmerer, K., Frei, E. & Marano, G., 2013, 14th EuCheMS International Conference on Chemistry and the Environment: Book of abstracts. European Association of Chemical and Molecular Sciences (EuCheMS) / Division of Chemistry and the Environment (DCE), p. 423 1 p.Research output: Contributions to collected editions/works › Published abstract in conference proceedings › Research › peer-review
- Published
Emerging pollutants: of old compounds and new ones, of micrograms and tonnes, from the past to the future
Kümmerer, K., 2013, 14th EuCheMS International Conference on Chemistry and the Environment: ICCE 2013, Barcelona, June 25 - 28, 2013; Book of abstracts. European Association of Chemical and Molecular Sciences (EuCheMS) / Division of Chemistry and the Environment (DCE), p. 42 1 p.Research output: Contributions to collected editions/works › Published abstract in conference proceedings › Research › peer-review
- Published
A sustainable chemistry solution to the presence of pharmaceuticals and chemicals in the aquatic environment-the example of re-designing β-blocker Atenolol
Rastogi, T., Leder, C. & Kummerer, K., 2015, In: RSC Advances. 5, 1, p. 27-32 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Photodegradation of the antineoplastic cyclophosphamide: A comparative study of the efficiencies of UV/H2O2, UV/Fe(2+)/H2O2 and UV/TiO2 processes
Lutterbeck, C. A., Machado, E. L. & Kümmerer, K., 01.02.2015, In: Chemosphere. 120, p. 538-546 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Emerging risks from ballast water treatment: The run-up to the International Ballast Water Management Convention
Werschkun, B., Banerji, S., Basurko, O. C., David, M., Fuhr, F., Gollasch, S., Grummt, T., Haarich, M., Jha, A. N., Kacan, S., Kehrer, A., Linders, J., Mesbahi, E., Pughiuc, D., Richardson, S. D., Schwarz-Schulz, B., Shah, A., Theobald, N., von Gunten, U., Wieck, S. & Höfer, T., 01.10.2014, In: Chemosphere. 112, p. 256-266 11 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Recalcitrant pharmaceuticals in the aquatic environment: A comparative screening study of their occurrence, formation of phototransformation products and their in vitro toxicity
Bergheim, M., Gminski, R., Spangenberg, B., Dȩbiak, M., Bürkle, A., Mersch-Sundermann, V., Kümmerer, K. & Gieré, R., 2014, In: Environmental Chemistry. 11, 4, p. 431-444 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Environmental side effects of pharmaceutical cocktails: What we know and what we should know
Vasquez, M. I., Lambrianides, A., Schneider, M., Kümmerer, K. & Fatta-Kassinos, D., 30.08.2014, In: Journal of Hazardous Materials. 279, p. 169-189 21 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Designing green derivatives of β-blocker Metoprolol: A tiered approach for green and sustainable pharmacy and chemistry
Rastogi, T., Leder, C. & Kümmerer, K., 01.09.2014, In: Chemosphere. 111, p. 493-499 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Occurrence of the antidiabetic drug Metformin and its ultimate transformation product Guanylurea in several compartments of the aquatic cycle
Trautwein, C., Berset, J-D., Wolschke, H. & Kümmerer, K., 09.2014, In: Environmental international. 70, p. 203-212 10 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Fate of phenothiazine pharmaceuticals during Fenton process: experimental design optimization, assessment of transformation products and ready biodegradability
Wilde, M. L. & Kümmerer, K., 04.06.2014, Abstract book of the 2nd international conference on recycling and reuse: June 4-6, 2014-İstanbul/ Türkiye. Bekbölet, M., Selcuk, H., Kavurmaci, S. S., Aydin, I., Yüzer, B. & Yigit Hunce, S. (eds.). Boğaziçi University Press, p. 103-104 2 p.Research output: Contributions to collected editions/works › Published abstract in conference proceedings › Research › peer-review
- Published
Germany – Europe –World 2042: A Transformative Longitudinal Study
Bergmann, M., Burandt, S., Heinrichs, H., Kümmerer, K. & Lang, D. J., 05.2014, In: GAIA. 23, 2, p. 132-134 3 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Helical [n]catamantanes and all-trans-perhydroacenic [n]perimantanes: Structures and von Baeyer IUPAC numbering of carbon atoms
Balaban, A. T. & Rücker, C., 19.12.2013, In: Arkivoc. 2014, 2, p. 346-361 16 p., CV-8352NP.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Mathematical Chemistry and Chemoinformatics: Structure Generation, Elucidation and Quantitative Structure-Property Relationships
Kerber, A., Laue, R., Meringer, M., Rücker, C. & Schymanski, E., 01.01.2014, 1 ed. Berlin: Walter de Gruyter GmbH. 521 p.Research output: Books and anthologies › Book
- Published
Characterization of photo-transformation products of the antibiotic drug Ciprofloxacin with liquid chromatography-tandem mass spectrometry in combination with accurate mass determination using an LTQ-Orbitrap
Haddad, T. & Kümmerer, K., 11.2014, In: Chemosphere. 115, 1, p. 40-46 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Qualitative environmental risk assessment of photolytic transformation products of iodinated X-ray contrast agent diatrizoic acid
Rastogi, T., Leder, C. & Kümmerer, K., 01.06.2014, In: The Science of The Total Environment. 482-483, 1, p. 378-388 11 p.Research output: Journal contributions › Journal articles › Research › peer-review