Professorship for Sustainable Chemistry and Material Resources
Organisational unit: Section
Organisation profile
RESEARCH AND TEACHING
Chair for Sustainable Chemistry and Material Resources
We research and train in the field of sustainable chemistry and pharmacy.
We focus on environmental questions as well as on sustainable questions going beyond that such as social and ecological aspects in the context of the life cycle of chemical substances and products. This includes the extraction of raw material, its use as well as the fate after its use. We are also interested in the material flow associated with the extraction and use of the raw material. On top of the experimental work and modeling, we also develop concepts as for example Benign by Design intended dissipation.
Our research and teaching is carried out on an intra- and transdisciplinary scale within the Faculty of Sustainability together with national and international co-operations.
Topics
We are interested in environmental affairs and all questions concerning the sustainability within the context of the life cycle of chemicals, starting with the raw material itself and going on to the synthesis, the use to end up with the environmental fate of chemical substances and products after their use. Beyond the chemical substances and products themselves, we are also interested in the associated material flows, especially when it comes to the so-called strategic resources (e. g. phosphate, seldom metals).
We investigate the fate (e. g. identification of relevant sources) in the environment as well as the spread and the behavior of chemicals (e. g. spread, biological and photochemical degradation) in the aquatic environment in the sense of a sustainable water management. This is why we want to record their effects (e. g. genotoxicity, mutagenity, and bacteria toxicity).At present we are focusing on pesticides, pharmaceuticals, textile auxiliary agents and nanoparticles.
Service offers
Examination of (bio)-degradability of chemicals and pharmaceuticals
according to OECD/DIN/ISO and others:
• Closed Bottle-Test (OECD 301 D)
• Manometric Respirometry (OECD 301 F)
• Zahn-Wellens-Test (OECD 302 B)
• Waste water treatment plant simulation (OECD 303 A)
• Water Sediment Test
• Photochemical degradation
• Photocatalytic degradation
• Electro coalugation
• and other
Toxicity
Acute and chronic toxicity in bacteria:
• Luminescent bacteria test with Vibrio fischeri (30 minutes and 20h)
• Growth-inhibition test with Pseudomonas putida (16h) and Vibrio fischeri (20h)
• Growth-inhibition test with Enteroccus faecalis
Genotoxicity:
• Ames-Test with Salmonella typhimurium TA 98/TA 100
• Umu-Test with Salmonella typhimurium TA 1535/ psK 1002
• Mikronucleus-Test with CHO-Cells by FACS-Analysis
• Green Screen-Assay with TK6-cells
Chemical informatics
Structure property relationships
• Calculation of physicochemical properties of molecules
• Calculation of quantum chemical parameters of molecules
• Calculation of toxicity and mutagenicity
• Calculation of the biological degradation
• Calculation of metabolites (mammalia bacteria)
• Targeted design of chemicals and pharmaceuticals
• Support in purchasing decisions
• Product optimization
• REACH
Water flux based reactive mass transport modelling and assessment
• Spatio-temporal analysis of discharge and water quality (R-Statistics, SigmaPlot, ArcGIS)
• Assessment of water quality by combined water quality and quantity indices (WQI, WQQI, WAI)
• Water quality modelling in lakes and reservoirs in 1D, 2D and 3D (LAC, MOHID Water, Ce-qual)
• Catchment modelling of hydrology, erosion and sedimenttransport, phosphorus discharge, pesticides and transformation product discharge (ZIN-Sed, MOHID Land, reservoir models)
• River channel modelling of water, sediment, phosphorus, pesticide and transformation product discharge (ZIN-Sed, MOHID Stream)
• Scenario modelling and assessment
• System analysis and management assessment
• Integrated water ressources management
Analytics
• Liquid chromatography coupled to ion trap mass spectrometry
• HPLC with UV and fluorescence detection
• Gas chromatography coupled to mass spectrometry
• Ion chromatography
- Journal articles › Research › Peer-reviewed
- Published
Occurrence, distribution, and ecotoxicological risk assessment of selected pharmaceutical compounds in water from Lake Victoria, Uganda
Nantaba, F., Wasswa, J., Kylin, H., Palm, W. U., Bouwman, H. & Kümmerer, K., 01.01.2020, In: Chemosphere. 239, 124642.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Occurrence of the antidiabetic drug Metformin and its ultimate transformation product Guanylurea in several compartments of the aquatic cycle
Trautwein, C., Berset, J-D., Wolschke, H. & Kümmerer, K., 09.2014, In: Environmental international. 70, p. 203-212 10 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Octanol-Water Partition Coefficient Measurement by a Simple 1H NMR Method
Cumming, H. & Rücker, C., 30.09.2017, In: ACS Omega. 2, 9, p. 6244-6249 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Optimization and validation of an HPLC-UV method for determination of tranexamic acid in a dosage form and in human urine.
Hadad, G. M., El-Gindy, A. & Mahmoud, W. M. M., 09.2007, In: Chromatographia. 66, 5-6, p. 311-317 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Optimization and Validation of an LC Method for the Determination of Cefdinir in Dosage Form and Human Urine
Hadad, G. M., Emara, S. & Mahmoud, W. M. M., 12.2009, In: Chromatographia. 70, 11/12, p. 1593–1598 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Oxidation-coagulation of β-blockers by K2Fe(VI)O4 in hospital wastewater: Assessment of degradation products and biodegradability
Wilde, M. L., Mahmoud, W. M. M., Kümmerer, K. & Martins, A. F., 01.05.2013, In: The Science of The Total Environment. 452-453, p. 137-147 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
PharmCycle: a holistic approach to reduce the contamination of the aquatic environment with antibiotics by developing sustainable antibiotics, improving the environmental risk assessment of antibiotics, and reducing the discharges of antibiotics in the wastewater outlet
Andrae, J., Beyer, F., Cornelissen, G., Einfeldt, J., Heseding, J., Kuemmerer, K., Oelkers, K. & Floeter, C., 01.12.2018, In: Environmental Sciences Europe. 30, 1, 15 p., 24.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Photodegradation of micropollutants using V-UV/UV-C processes: Triclosan as a model compound
Alfiya, Y., Friedler, E., Westphal, J., Olsson, O. & Dubowski, Y., 01.12.2017, In: The Science of The Total Environment. 601-602, p. 397-404 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Photodegradation of the antineoplastic cyclophosphamide: A comparative study of the efficiencies of UV/H2O2, UV/Fe(2+)/H2O2 and UV/TiO2 processes
Lutterbeck, C. A., Machado, E. L. & Kümmerer, K., 01.02.2015, In: Chemosphere. 120, p. 538-546 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Photodegradation of the UV filter ethylhexyl methoxycinnamate under ultraviolet light: identification and in silico assessment of photo-transformation products in the context of grey water reuse
Jentzsch, F., Olsson, O., Westphal, J., Reich, M., Leder, C. & Kümmerer, K., 01.12.2016, In: The Science of The Total Environment. 572, p. 1092-1100 9 p.Research output: Journal contributions › Journal articles › Research › peer-review