Professorship for Sustainable Chemistry and Material Resources
Organisational unit: Section
Organisation profile
RESEARCH AND TEACHING
Chair for Sustainable Chemistry and Material Resources
We research and train in the field of sustainable chemistry and pharmacy.
We focus on environmental questions as well as on sustainable questions going beyond that such as social and ecological aspects in the context of the life cycle of chemical substances and products. This includes the extraction of raw material, its use as well as the fate after its use. We are also interested in the material flow associated with the extraction and use of the raw material. On top of the experimental work and modeling, we also develop concepts as for example Benign by Design intended dissipation.
Our research and teaching is carried out on an intra- and transdisciplinary scale within the Faculty of Sustainability together with national and international co-operations.
Topics
We are interested in environmental affairs and all questions concerning the sustainability within the context of the life cycle of chemicals, starting with the raw material itself and going on to the synthesis, the use to end up with the environmental fate of chemical substances and products after their use. Beyond the chemical substances and products themselves, we are also interested in the associated material flows, especially when it comes to the so-called strategic resources (e. g. phosphate, seldom metals).
We investigate the fate (e. g. identification of relevant sources) in the environment as well as the spread and the behavior of chemicals (e. g. spread, biological and photochemical degradation) in the aquatic environment in the sense of a sustainable water management. This is why we want to record their effects (e. g. genotoxicity, mutagenity, and bacteria toxicity).At present we are focusing on pesticides, pharmaceuticals, textile auxiliary agents and nanoparticles.
Service offers
Examination of (bio)-degradability of chemicals and pharmaceuticals
according to OECD/DIN/ISO and others:
• Closed Bottle-Test (OECD 301 D)
• Manometric Respirometry (OECD 301 F)
• Zahn-Wellens-Test (OECD 302 B)
• Waste water treatment plant simulation (OECD 303 A)
• Water Sediment Test
• Photochemical degradation
• Photocatalytic degradation
• Electro coalugation
• and other
Toxicity
Acute and chronic toxicity in bacteria:
• Luminescent bacteria test with Vibrio fischeri (30 minutes and 20h)
• Growth-inhibition test with Pseudomonas putida (16h) and Vibrio fischeri (20h)
• Growth-inhibition test with Enteroccus faecalis
Genotoxicity:
• Ames-Test with Salmonella typhimurium TA 98/TA 100
• Umu-Test with Salmonella typhimurium TA 1535/ psK 1002
• Mikronucleus-Test with CHO-Cells by FACS-Analysis
• Green Screen-Assay with TK6-cells
Chemical informatics
Structure property relationships
• Calculation of physicochemical properties of molecules
• Calculation of quantum chemical parameters of molecules
• Calculation of toxicity and mutagenicity
• Calculation of the biological degradation
• Calculation of metabolites (mammalia bacteria)
• Targeted design of chemicals and pharmaceuticals
• Support in purchasing decisions
• Product optimization
• REACH
Water flux based reactive mass transport modelling and assessment
• Spatio-temporal analysis of discharge and water quality (R-Statistics, SigmaPlot, ArcGIS)
• Assessment of water quality by combined water quality and quantity indices (WQI, WQQI, WAI)
• Water quality modelling in lakes and reservoirs in 1D, 2D and 3D (LAC, MOHID Water, Ce-qual)
• Catchment modelling of hydrology, erosion and sedimenttransport, phosphorus discharge, pesticides and transformation product discharge (ZIN-Sed, MOHID Land, reservoir models)
• River channel modelling of water, sediment, phosphorus, pesticide and transformation product discharge (ZIN-Sed, MOHID Stream)
• Scenario modelling and assessment
• System analysis and management assessment
• Integrated water ressources management
Analytics
• Liquid chromatography coupled to ion trap mass spectrometry
• HPLC with UV and fluorescence detection
• Gas chromatography coupled to mass spectrometry
• Ion chromatography
- Published
Initial fate assessment of teratogenic drug trimipramine and its photo-transformation products - Role of pH, concentration and temperature
Khaleel, N. D. H., Mahmoud, W. M. M., Olsson, O. & Kümmerer, K., 01.01.2017, In: Water Research. 108, p. 197-211 15 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Inhibition of foam cell formation using a soluble CD68-Fc fusion protein
Daub, K., Siegel-Axel, D., Schönberger, T., Leder, C., Seizer, P., Müller, K., Schaller, M., Penz, S., Menzel, D., Buchele, B., Bültmann, A., Münch, G., Lindemann, S., Simmet, T. & Gawaz, M., 09.2010, In: Journal of Molecular Medicine. 88, 9, p. 909-920 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
IN DER UMWELT ABBAUBARE CHINOLON-ANTIBIOTIKA MIT HEMIAMINAL-STRUKTUREINHEIT
Kümmerer, K., Leder, C., Rastogi, T., Suk, M. & Peifer, C., 18.04.2019, IPC No. A61K31/47, A61P31/04 , C07D405/06, Europäisches Patentamt, Patent No. WO2019072905A1, 10.10.2018, Priority date 11.10.2017, Priority No. DE102017218119AResearch output: Patents › Patent
- Published
Incomplete aerobic degradation of the antidiabetic drug Metformin and identification of the bacterial dead-end transformation product Guanylurea
Trautwein, C. & Kümmerer, K., 10.2011, In: Chemosphere. 85, 5, p. 765-773 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Improving the end-of-life management of solar panels in Germany
El-Khawad, L., Bartkowiak, D. & Kümmerer, K., 01.10.2022, In: Renewable and Sustainable Energy Reviews. 168, 112678.Research output: Journal contributions › Journal articles › Research
- Published
Impact of green and blue-green light on the growth, pigment concentration, and fatty acid unsaturation in the microalga Monoraphidium braunii
Helamieh, M., Reich, M., Rohne, P., Riebesell, U., Kerner, M. & Kümmerer, K., 01.05.2024, In: Photochemistry and Photobiology. 100, 3, p. 587-595 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Identifizierung und Bewertung ausgewählter Arzneimittel und ihrer Metaboliten (Ab- und Umbauprodukte) im Wasserkreislauf
Kümmerer, K., Schuster, A., Längin, A., Happel, O., Thoma, A., Schneider, K., Hassauer, M., Gartiser, S. & Hafner, C., 01.08.2011, Dessau-Roßlau: Umweltbundesamt, 195 p. (Texte; vol. 46/2011).Research output: Working paper › Project reports › Transfer
- Published
Identification of structure-biodegradability relationships for ionic liquids - clustering of a dataset based on structural similarity
Amsel, A. K., Olsson, O. & Kümmerer, K., 29.09.2023, In: Green Chemistry . 25, 22, p. 9226-9250 25 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Identification of phototransformation products of the antiepileptic drug gabapentin: Biodegradability and initial assessment of toxicity
Herrmann, M., Menz, J., Olsson, O. & Kümmerer, K., 15.11.2015, In: Water Research. 85, p. 11-21 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Identification of phototransformation products of thalidomide and mixture toxicity assessment: An experimental and quantitative structural activity relationships (QSAR) approach
Mahmoud, W. M. M., Toolaram, A. P., Menz, J., Leder, C., Schneider, M. & Kümmerer, K., 01.02.2014, In: Water Research. 49, 1, p. 11-22 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Identification of environmentally biodegradable scaffolds for the benign design of quinolones and related substances
Suk, M., Lorenz, S. & Kümmerer, K., 01.04.2023, In: Sustainable Chemistry and Pharmacy. 31, 100947.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Identification of a heparin-binding motif on adeno-associated virus type 2 capsids
Kern, A., Schmidt, K., Leder, C., Müller, O., Wobus, C. E., Bettinger, K., von der Lieth, C. W., King, J. A. & Kleinschmidt, J. A., 15.10.2003, In: Journal of Virology. 77, 20, p. 11072–11081 10 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Identification and initial toxicity assessment of Thalidomide and its phototransformation products
Mahmoud, W. M. M., Toolaram, A. P., Menz, J., Leder, C., Schneider, M. & Kümmerer, K., 2013, 14th EuCheMS International Conference on Chemistry and the Environment. European Association for Chemical and Molecular Sciences / Division of Organic Chemistry, p. 366 1 p.Research output: Contributions to collected editions/works › Published abstract in conference proceedings › Research › peer-review
- Published
Hydrological tracers for assessing transport and dissipation processes of pesticides in a model constructed wetland system
Fernández-Pascual, E., Bork, M., Hensen, B. & Lange, J., 08.01.2020, In: Hydrology and Earth System Sciences. 24, 1, p. 41-60 20 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Hydraulic Fracturing: Zusammensetzung und Entsorgung anfallender Abwässer
Olsson, O., Weichgrebe, D. & Rosenwinkel, K-H., 09.2012, In: Wasser und Abfall. 14, 9, p. 10-15 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Hydraulic fracturing wastewater in Germany: Composition, treatment, concerns
Olsson, O., Weichgrebe, D. & Rosenwinkel, K-H., 12.2013, In: Environmental Earth Sciences . 70, 8, p. 3895-3906 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Human and veterinary drugs in the environment
Rastogi, T., Ahmed, W. M. M. M. & Kümmerer, K., 01.01.2017, Encyclopedia of the Anthropocene. Elsevier B.V., Vol. 1-5. p. 263-268 6 p.Research output: Contributions to collected editions/works › Articles for encyclopedia › Research
- Published
HPLC and chemometrics-assisted UV-spectroscopy methods for the simultaneous determination of ambroxol and doxycycline in capsule.
Hadad, G. M., El-Gindy, A. & Mahmoud, W. M. M., 08.2008, In: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 70, 3, p. 655-663 9 p.Research output: Journal contributions › Journal articles › Research
- Published
How to specify the structure of substituted blade-like zigzag diamondoids
Balaban, A. T. & Rücker, C., 09.2013, In: Central European Journal of Chemistry. 11, 9, p. 1423-1430 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
How data on transformation products can support the redesign of sulfonamides towards better biodegradability in the environment
Puhlmann, N., Olsson, O. & Kümmerer, K., 15.04.2024, In: Science of the Total Environment. 921, 13 p., 171027.Research output: Journal contributions › Journal articles › Research › peer-review