Mechanical characterisation and modelling of electrospun materials for biomedical applications
Publikation: Beiträge in Sammelwerken › Aufsätze in Konferenzbänden › Forschung › begutachtet
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2015 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2015 - Proceedings. IEEE - Institute of Electrical and Electronics Engineers Inc., 2015. S. 507-511.
Publikation: Beiträge in Sammelwerken › Aufsätze in Konferenzbänden › Forschung › begutachtet
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TY - CHAP
T1 - Mechanical characterisation and modelling of electrospun materials for biomedical applications
AU - Polak, Katarzyna
AU - Georgiadis, Anthimos
AU - Heikkila, Pirjo
N1 - Conference code: 10
PY - 2015
Y1 - 2015
N2 - Electrospun nonwovens, due to their intrinsic beneficial properties, have found many applications in biomedical areas such as tissue engineering, drug delivery, or active wound management. Exploiting its porous structure, electrospun is often used as scaffolds for tissue growth which can be stimulated by mechanical properties of the structure. Cells proliferation can be controlled by stress distribution in the scaffold, thus improving its efficiency. Anticipation of this parameter is possible by using Finite Elements Model of electrospun structure presented in this study. Fully parametric model of nonwoven material with random fibrous distribution was developed enabling the calculation of mechanical properties of material on the basis of input parameters such as mechanical characteristics and geometry of single component fibres. Relatively low production ratio of electrospinning process and time consuming characterisation methods were motivation to develop the tool that would shorten the design and optimisation of electrospun materials. The model was validated experimentally by mechanical testing of electrospun material; modelling and experimental results were in a good agreement.
AB - Electrospun nonwovens, due to their intrinsic beneficial properties, have found many applications in biomedical areas such as tissue engineering, drug delivery, or active wound management. Exploiting its porous structure, electrospun is often used as scaffolds for tissue growth which can be stimulated by mechanical properties of the structure. Cells proliferation can be controlled by stress distribution in the scaffold, thus improving its efficiency. Anticipation of this parameter is possible by using Finite Elements Model of electrospun structure presented in this study. Fully parametric model of nonwoven material with random fibrous distribution was developed enabling the calculation of mechanical properties of material on the basis of input parameters such as mechanical characteristics and geometry of single component fibres. Relatively low production ratio of electrospinning process and time consuming characterisation methods were motivation to develop the tool that would shorten the design and optimisation of electrospun materials. The model was validated experimentally by mechanical testing of electrospun material; modelling and experimental results were in a good agreement.
KW - electrospinning
KW - FEM
KW - modelling
KW - nonwoven
KW - tensile testing
KW - Engineering
UR - http://www.scopus.com/inward/record.url?scp=84939545896&partnerID=8YFLogxK
U2 - 10.1109/MeMeA.2015.7145256
DO - 10.1109/MeMeA.2015.7145256
M3 - Article in conference proceedings
AN - SCOPUS:84939545896
SN - 978-1-4799-6476-5
SP - 507
EP - 511
BT - 2015 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2015 - Proceedings
PB - IEEE - Institute of Electrical and Electronics Engineers Inc.
T2 - 10th IEEE International Symposium on Medical Measurements and Applications - MeMeA 2015
Y2 - 7 May 2015 through 9 May 2015
ER -