TY - CHAP

T1 - Mechanical characterisation and modelling of electrospun materials for biomedical applications

AU - Polak, Katarzyna

AU - Georgiadis, Anthimos

AU - Heikkila, Pirjo

N1 - Conference code: 10

PY - 2015

Y1 - 2015

N2 - Electrospun nonwovens, due to their intrinsic beneficial properties, have found many applications in biomedical areas such as tissue engineering, drug delivery, or active wound management. Exploiting its porous structure, electrospun is often used as scaffolds for tissue growth which can be stimulated by mechanical properties of the structure. Cells proliferation can be controlled by stress distribution in the scaffold, thus improving its efficiency. Anticipation of this parameter is possible by using Finite Elements Model of electrospun structure presented in this study. Fully parametric model of nonwoven material with random fibrous distribution was developed enabling the calculation of mechanical properties of material on the basis of input parameters such as mechanical characteristics and geometry of single component fibres. Relatively low production ratio of electrospinning process and time consuming characterisation methods were motivation to develop the tool that would shorten the design and optimisation of electrospun materials. The model was validated experimentally by mechanical testing of electrospun material; modelling and experimental results were in a good agreement.

AB - Electrospun nonwovens, due to their intrinsic beneficial properties, have found many applications in biomedical areas such as tissue engineering, drug delivery, or active wound management. Exploiting its porous structure, electrospun is often used as scaffolds for tissue growth which can be stimulated by mechanical properties of the structure. Cells proliferation can be controlled by stress distribution in the scaffold, thus improving its efficiency. Anticipation of this parameter is possible by using Finite Elements Model of electrospun structure presented in this study. Fully parametric model of nonwoven material with random fibrous distribution was developed enabling the calculation of mechanical properties of material on the basis of input parameters such as mechanical characteristics and geometry of single component fibres. Relatively low production ratio of electrospinning process and time consuming characterisation methods were motivation to develop the tool that would shorten the design and optimisation of electrospun materials. The model was validated experimentally by mechanical testing of electrospun material; modelling and experimental results were in a good agreement.

KW - electrospinning

KW - FEM

KW - modelling

KW - nonwoven

KW - tensile testing

KW - Engineering

UR - http://www.scopus.com/inward/record.url?scp=84939545896&partnerID=8YFLogxK

U2 - 10.1109/MeMeA.2015.7145256

DO - 10.1109/MeMeA.2015.7145256

M3 - Article in conference proceedings

AN - SCOPUS:84939545896

SN - 978-1-4799-6476-5

SP - 507

EP - 511

BT - 2015 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2015 - Proceedings

PB - IEEE - Institute of Electrical and Electronics Engineers Inc.

T2 - 10th IEEE International Symposium on Medical Measurements and Applications - MeMeA 2015

Y2 - 7 May 2015 through 9 May 2015

ER -