Element distribution in the corrosion layer and cytotoxicity of alloy Mg-10Dy during in vitro biodegradation

Publikation: Beiträge in ZeitschriftenZeitschriftenaufsätzeForschungbegutachtet

Standard

Element distribution in the corrosion layer and cytotoxicity of alloy Mg-10Dy during in vitro biodegradation. / Yang, Lei; Hort, Norbert; Laipple, Daniel et al.
in: Acta Biomaterialia, Jahrgang 9, Nr. 10, 11.2013, S. 8475-8487.

Publikation: Beiträge in ZeitschriftenZeitschriftenaufsätzeForschungbegutachtet

Harvard

Yang, L, Hort, N, Laipple, D, Höche, D, Huang, Y, Kainer, KU, Willumeit, R & Feyerabend, F 2013, 'Element distribution in the corrosion layer and cytotoxicity of alloy Mg-10Dy during in vitro biodegradation', Acta Biomaterialia, Jg. 9, Nr. 10, S. 8475-8487. https://doi.org/10.1016/j.actbio.2012.10.001

APA

Yang, L., Hort, N., Laipple, D., Höche, D., Huang, Y., Kainer, K. U., Willumeit, R., & Feyerabend, F. (2013). Element distribution in the corrosion layer and cytotoxicity of alloy Mg-10Dy during in vitro biodegradation. Acta Biomaterialia, 9(10), 8475-8487. https://doi.org/10.1016/j.actbio.2012.10.001

Vancouver

Yang L, Hort N, Laipple D, Höche D, Huang Y, Kainer KU et al. Element distribution in the corrosion layer and cytotoxicity of alloy Mg-10Dy during in vitro biodegradation. Acta Biomaterialia. 2013 Nov;9(10):8475-8487. doi: 10.1016/j.actbio.2012.10.001

Bibtex

@article{3e680135de344ac88dbf2fb5c626cf48,
title = "Element distribution in the corrosion layer and cytotoxicity of alloy Mg-10Dy during in vitro biodegradation",
abstract = "The present work investigates the corrosion behaviour, the element distribution in the corrosion layer and the cytocompatibility of alloy Mg-10Dy. The corrosion experiments were performed in a cell culture medium (CCM) under cell culture conditions close to the in vivo environment. The element distribution on the surface as well as in cross-sections of the corrosion layer was investigated using scanning electron microscopy, energy-dispersive X-ray analysis, X-ray photoelectron spectroscopy and X-ray diffraction. The cytocompatibility of alloy Mg-10Dy with primary human osteoblasts was evaluated by MTT, cell adhesion and live/dead staining tests. The results show that the corrosion layer was enriched in Dy, while the P and Ca content gradually decreased from the surface to the bottom of the corrosion layer. In addition, large amounts of MgCO3·3H2O formed in the corrosion layer after 28 days immersion. Both extracts and the Dy-enriched corrosion layer of alloy Mg-10Dy showed no cytotoxicity to primary human osteoblasts.",
keywords = "Cytocompatibility, Element distribution, In vitro corrosion, Mg-10Dy alloy, Engineering",
author = "Lei Yang and Norbert Hort and Daniel Laipple and Daniel H{\"o}che and Yuanding Huang and Kainer, {Karl Ulrich} and Regine Willumeit and Frank Feyerabend",
year = "2013",
month = nov,
doi = "10.1016/j.actbio.2012.10.001",
language = "English",
volume = "9",
pages = "8475--8487",
journal = "Acta Biomaterialia",
issn = "1742-7061",
publisher = "Acta Materialia Inc",
number = "10",

}

RIS

TY - JOUR

T1 - Element distribution in the corrosion layer and cytotoxicity of alloy Mg-10Dy during in vitro biodegradation

AU - Yang, Lei

AU - Hort, Norbert

AU - Laipple, Daniel

AU - Höche, Daniel

AU - Huang, Yuanding

AU - Kainer, Karl Ulrich

AU - Willumeit, Regine

AU - Feyerabend, Frank

PY - 2013/11

Y1 - 2013/11

N2 - The present work investigates the corrosion behaviour, the element distribution in the corrosion layer and the cytocompatibility of alloy Mg-10Dy. The corrosion experiments were performed in a cell culture medium (CCM) under cell culture conditions close to the in vivo environment. The element distribution on the surface as well as in cross-sections of the corrosion layer was investigated using scanning electron microscopy, energy-dispersive X-ray analysis, X-ray photoelectron spectroscopy and X-ray diffraction. The cytocompatibility of alloy Mg-10Dy with primary human osteoblasts was evaluated by MTT, cell adhesion and live/dead staining tests. The results show that the corrosion layer was enriched in Dy, while the P and Ca content gradually decreased from the surface to the bottom of the corrosion layer. In addition, large amounts of MgCO3·3H2O formed in the corrosion layer after 28 days immersion. Both extracts and the Dy-enriched corrosion layer of alloy Mg-10Dy showed no cytotoxicity to primary human osteoblasts.

AB - The present work investigates the corrosion behaviour, the element distribution in the corrosion layer and the cytocompatibility of alloy Mg-10Dy. The corrosion experiments were performed in a cell culture medium (CCM) under cell culture conditions close to the in vivo environment. The element distribution on the surface as well as in cross-sections of the corrosion layer was investigated using scanning electron microscopy, energy-dispersive X-ray analysis, X-ray photoelectron spectroscopy and X-ray diffraction. The cytocompatibility of alloy Mg-10Dy with primary human osteoblasts was evaluated by MTT, cell adhesion and live/dead staining tests. The results show that the corrosion layer was enriched in Dy, while the P and Ca content gradually decreased from the surface to the bottom of the corrosion layer. In addition, large amounts of MgCO3·3H2O formed in the corrosion layer after 28 days immersion. Both extracts and the Dy-enriched corrosion layer of alloy Mg-10Dy showed no cytotoxicity to primary human osteoblasts.

KW - Cytocompatibility

KW - Element distribution

KW - In vitro corrosion

KW - Mg-10Dy alloy

KW - Engineering

UR - http://www.scopus.com/inward/record.url?scp=84884675978&partnerID=8YFLogxK

U2 - 10.1016/j.actbio.2012.10.001

DO - 10.1016/j.actbio.2012.10.001

M3 - Journal articles

C2 - 23063554

AN - SCOPUS:84884675978

VL - 9

SP - 8475

EP - 8487

JO - Acta Biomaterialia

JF - Acta Biomaterialia

SN - 1742-7061

IS - 10

ER -

DOI

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