TY - JOUR

T1 - Chemical surface alteration of biodegradable magnesium exposed to corrosion media

AU - Willumeit, Regine

AU - Fischer, Janine

AU - Feyerabend, Frank

AU - Hort, Norbert

AU - Bismayer, Ulrich

AU - Heidrich, Stefanie

AU - Mihailova, Boriana

PY - 2011/6

Y1 - 2011/6

N2 - The understanding of corrosion processes of metal implants in the human body is a key problem in modern biomaterial science. Because of the complicated and adjustable in vivo environment, in vitro experiments require the analysis of various physiological corrosion media to elucidate the underlying mechanism of "biological" metal surface modification. In this paper magnesium samples were incubated under cell culture conditions (i.e. including CO 2) in electrolyte solutions and cell growth media, with and without proteins. Chemical mapping by high-resolution electron-induced X-ray emission spectroscopy and infrared reflection microspectroscopy revealed a complex structure of the formed corrosion layer. The presence of CO2 in concentrations close to that in blood is significant for the chemistry of the oxidised layer. The presence of proteins leads to a less dense but thicker passivation layer which is still ion and water permeable, as osmolality and weight measurements indicate.

AB - The understanding of corrosion processes of metal implants in the human body is a key problem in modern biomaterial science. Because of the complicated and adjustable in vivo environment, in vitro experiments require the analysis of various physiological corrosion media to elucidate the underlying mechanism of "biological" metal surface modification. In this paper magnesium samples were incubated under cell culture conditions (i.e. including CO 2) in electrolyte solutions and cell growth media, with and without proteins. Chemical mapping by high-resolution electron-induced X-ray emission spectroscopy and infrared reflection microspectroscopy revealed a complex structure of the formed corrosion layer. The presence of CO2 in concentrations close to that in blood is significant for the chemistry of the oxidised layer. The presence of proteins leads to a less dense but thicker passivation layer which is still ion and water permeable, as osmolality and weight measurements indicate.

KW - Chemical element mapping

KW - Corrosion layer

KW - IR reflection microspectroscopy

KW - Magnesium

KW - Physiological corrosion

KW - Engineering

UR - http://www.scopus.com/inward/record.url?scp=79955581562&partnerID=8YFLogxK

U2 - 10.1016/j.actbio.2011.03.004

DO - 10.1016/j.actbio.2011.03.004

M3 - Journal articles

C2 - 21382530

AN - SCOPUS:79955581562

VL - 7

SP - 2704

EP - 2715

JO - Acta Biomaterialia

JF - Acta Biomaterialia

SN - 1742-7061

IS - 6

ER -