Professorship for Sustainable Chemistry and Material Resources
Organisational unit: Section
Organisation profile
RESEARCH AND TEACHING
Chair for Sustainable Chemistry and Material Resources
We research and train in the field of sustainable chemistry and pharmacy.
We focus on environmental questions as well as on sustainable questions going beyond that such as social and ecological aspects in the context of the life cycle of chemical substances and products. This includes the extraction of raw material, its use as well as the fate after its use. We are also interested in the material flow associated with the extraction and use of the raw material. On top of the experimental work and modeling, we also develop concepts as for example Benign by Design intended dissipation.
Our research and teaching is carried out on an intra- and transdisciplinary scale within the Faculty of Sustainability together with national and international co-operations.
Topics
We are interested in environmental affairs and all questions concerning the sustainability within the context of the life cycle of chemicals, starting with the raw material itself and going on to the synthesis, the use to end up with the environmental fate of chemical substances and products after their use. Beyond the chemical substances and products themselves, we are also interested in the associated material flows, especially when it comes to the so-called strategic resources (e. g. phosphate, seldom metals).
We investigate the fate (e. g. identification of relevant sources) in the environment as well as the spread and the behavior of chemicals (e. g. spread, biological and photochemical degradation) in the aquatic environment in the sense of a sustainable water management. This is why we want to record their effects (e. g. genotoxicity, mutagenity, and bacteria toxicity).At present we are focusing on pesticides, pharmaceuticals, textile auxiliary agents and nanoparticles.
Service offers
Examination of (bio)-degradability of chemicals and pharmaceuticals
according to OECD/DIN/ISO and others:
• Closed Bottle-Test (OECD 301 D)
• Manometric Respirometry (OECD 301 F)
• Zahn-Wellens-Test (OECD 302 B)
• Waste water treatment plant simulation (OECD 303 A)
• Water Sediment Test
• Photochemical degradation
• Photocatalytic degradation
• Electro coalugation
• and other
Toxicity
Acute and chronic toxicity in bacteria:
• Luminescent bacteria test with Vibrio fischeri (30 minutes and 20h)
• Growth-inhibition test with Pseudomonas putida (16h) and Vibrio fischeri (20h)
• Growth-inhibition test with Enteroccus faecalis
Genotoxicity:
• Ames-Test with Salmonella typhimurium TA 98/TA 100
• Umu-Test with Salmonella typhimurium TA 1535/ psK 1002
• Mikronucleus-Test with CHO-Cells by FACS-Analysis
• Green Screen-Assay with TK6-cells
Chemical informatics
Structure property relationships
• Calculation of physicochemical properties of molecules
• Calculation of quantum chemical parameters of molecules
• Calculation of toxicity and mutagenicity
• Calculation of the biological degradation
• Calculation of metabolites (mammalia bacteria)
• Targeted design of chemicals and pharmaceuticals
• Support in purchasing decisions
• Product optimization
• REACH
Water flux based reactive mass transport modelling and assessment
• Spatio-temporal analysis of discharge and water quality (R-Statistics, SigmaPlot, ArcGIS)
• Assessment of water quality by combined water quality and quantity indices (WQI, WQQI, WAI)
• Water quality modelling in lakes and reservoirs in 1D, 2D and 3D (LAC, MOHID Water, Ce-qual)
• Catchment modelling of hydrology, erosion and sedimenttransport, phosphorus discharge, pesticides and transformation product discharge (ZIN-Sed, MOHID Land, reservoir models)
• River channel modelling of water, sediment, phosphorus, pesticide and transformation product discharge (ZIN-Sed, MOHID Stream)
• Scenario modelling and assessment
• System analysis and management assessment
• Integrated water ressources management
Analytics
• Liquid chromatography coupled to ion trap mass spectrometry
• HPLC with UV and fluorescence detection
• Gas chromatography coupled to mass spectrometry
• Ion chromatography
- Published
A kinetic study of the photolysis of sulfamethoxazole with special emphasis on the photoisomer
Palm, W. U., Schmidt, N., Stahn, M. & Grimme, S., 01.03.2023, In: Photochemical and Photobiological Sciences. 22, 3, p. 615-630 16 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
A modified epitope identified for generation and monitoring of PSA-specific T cells in patients on early phases of PSA-based immunotherapeutic protocols
Lundberg, K., Roos, A-K., Pavlenko, M., Leder, C., Wehrum, D., Guevara-Patiño, J., Andersen, R. S. & Pisa, P., 04.03.2009, In: Vaccine. 27, 10, p. 1557-1565 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Analyses of Drugs and Pharmaceuticals in the Environment
Ali, I., Aboul-Enein, H. Y. & Kümmerer, K., 05.07.2011, Biophysico-Chemical Processes of Anthropogenic Organic Compounds in Environmental Systems. Xing, B., Senesi, N. & Ming, P. (eds.). 1 ed. John Wiley & Sons Inc., p. 439-462 24 p.Research output: Contributions to collected editions/works › Chapter › peer-review
- Published
Analysis of environmental biodegradability of cellulose-based pharmaceutical excipients in aqueous media
Bading, M., Olsson, O. & Kümmerer, K., 01.03.2024, In: Chemosphere. 352, 8 p., 141298.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Angewandte Methodik bei der separaten Behandlung von Abwasser aus Einrichtungen des Gesundheitswesens
Mousel, D., Bastian, D., Everding, W., Firk, J., Bäumlisberger, M., Herrel, M., Herrmann, M., Menz, J. & Gebhardt, W., 2015, Abwasser aus Einrichtungen des Gesundheitswesens – Charakterisierung, Technologien, Kommunikation und Konzepte: Abschlussbericht des durch das Bundesministerium für Bildung und Forschung geförderten Vorhabens "Innovative Konzepte und Technologien für die separate Behandlung von Abwasser aus Einrichtungen des Gesundheitswesens (Sauber+)". Pinnekamp, J., Palmowski, L., Kümmerer, K. & Schramm, E. (eds.). Aachen: Gesellschaft zur Förderung der Siedlungswasserwirtschaft an der RWTH Aachen e.V., Vol. 238. p. 117-134 (Gewässerschutz - Wasser - Abwasser; vol. 238).Research output: Contributions to collected editions/works › Contributions to collected editions/anthologies › Research › peer-review
- Published
Antibiotic residues in livestock manure: Does the EU risk assessment sufficiently protect against microbial toxicity and selection of resistant bacteria in the environment?
Menz, J., Olsson, O. & Kümmerer, K., 05.11.2019, In: Journal of Hazardous Materials. 379, 120807.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Antibiotics and sweeteners in the aquatic environment: biodegradability, formation of phototransformation products, and in vitro toxicity
Bergheim, M., Gminski, R., Spangenberg, B., Debiak, M., Bürkle, A., Mersch-Sundermann, V., Kümmerer, K. & Gieré, R., 01.11.2015, In: Environmental Science and Pollution Research. 22, 22, p. 18017-18030 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Antibiotics in the Aquatic Environment
Kümmerer, K., 07.12.2011, Antimicrobial Resistance in the Environment. Keen, P. & Montforts, M. (eds.). 1. ed. Hoboken: John Wiley & Sons Ltd., p. 325-335 11 p.Research output: Contributions to collected editions/works › Chapter › peer-review
- Published
Antimicrobial activity of pharmaceutical cocktails in sewage treatment plant effluent: An experimental and predictive approach to mixture risk assessment
Menz, J., Baginska, E., Arrhenius, Å., Haiß, A., Backhaus, T. & Kümmerer, K., 01.12.2017, In: Environmental Pollution. 231, 2, p. 1507-1517 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Antineoplastic compounds in the environment: Substances of special concern
Kümmerer, K., Haiß, A., Schuster, A., Hein, A. & Ebert, I., 01.08.2016, In: Environmental Science and Pollution Research. 23, 15, p. 14791–14804 14 p.Research output: Journal contributions › Journal articles › Research › peer-review